Mouse Anti-TROVE2 Recombinant Antibody (CBYJT-4894) (CBMAB-T4440-YJ)

Name: Mouse Anti-TROVE2 Recombinant Antibody (CBYJT-4894)
SKU: CBMAB-T4440-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4894

Application

ELISA, IHC-P, WB

Immunogen

Recombinant protein

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TROVE domain family, member 2

Introduction

TROVE2 (TROVE Domain Family Member 2) is a Protein Coding gene. Diseases related to TROVE2 include Sjogren Syndrome and Heart Block, Congenital. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to TROVE2 include RNA binding and U2 snRNA binding.

Entrez Gene ID

6738

UniProt ID

P10155

Alternative Names

TROVE Domain Family Member 2; Sjoegren Syndrome Type A Antigen; 0 KDa Ribonucleoprotein Ro; RORNP; SSA2; RO60; Sjogren Syndrome Antigen A2 (60kDa, Ribonucleoprotein Autoantigen SS-A/Ro); Sjogren Syndrome Antigen A2 (60kD, Ribonucleoprotein Autoantigen SS-A/Ro)

Function

RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853).
Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853).
Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853).
May play roles in cilia formation and/or maintenance (By similarity).

Biological Process

Biological Process cellular response to interferon-alpha Source:UniProtKB1 Publication
Biological Process cilium assembly Source:Ensembl
Biological Process immune system development Source:Ensembl
Biological Process regulation of gene expression Source:UniProtKB1 Publication
Biological Process response to UV Source:Ensembl
Biological Process smoothened signaling pathway Source:Ensembl
Biological Process transcription by RNA polymerase III Source:ProtInc1 Publication

Cellular Location

Cytoplasm
Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-TROVE2 Recombinant Antibody (CBYJT-4893) (CAT#: CBMAB-T4439-YJ)

Mouse Anti-TROVE2 Recombinant Antibody (CBYJT-4892) (CAT#: CBMAB-T4438-YJ)

Mouse Anti-TROVE2 Recombinant Antibody (2G10) (CAT#: CBMAB-R4082-CN)

Mouse Anti-TROVE2 Recombinant Antibody (CBYJT-4891) (CAT#: CBMAB-T4437-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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