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Mouse Anti-RSPH1 Recombinant Antibody (3G6) (CBMAB-A9572-LY)

The product is antibody recognizes TSGA2. The antibody 3G6 immunoassay techniques such as: WB, ELISA.
See all RSPH1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TSGA2 (NP_543136, 200 a.a. ~ 309 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Radial Spoke Head 1 Homolog
Entrez Gene ID
89765
UniProt ID
Q8WYR4
Alternative Names
MGC126568; MGC141927; RSP44; RSPH10A; TSA2; TSGA2
Function
May play an important role in male meiosis (By similarity).
It is necessary for proper building of the axonemal central pair and radial spokes.
Biological Process
Biological Process axoneme assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process meiotic cell cycleIEA:UniProtKB-KW
Biological Process spermatid developmentManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cell projection, cilium
Cytoplasmic in late spermatocytes, secondary spermatocytes and round spermatids. Gathered around metaphase chromosomes during meiotic divisions (By similarity).
Involvement in disease
Ciliary dyskinesia, primary, 24 (CILD24):
A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Situs inversus is not observed in CILD24 patients.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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