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Rat Anti-TSLP Recombinant Antibody (28F12) (CBMAB-0119-CN)

This product is a rat antibody that recognizes TSLP of mouse. The antibody 28F12 can be used for immunoassay techniques such as: BL.
See all TSLP antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
28F12
Antibody Isotype
IgG2a
Application
Blocking

Basic Information

Immunogen
TSLP
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TSLP Gene(Protein Coding) Thymic Stromal Lymphopoietin
Introduction
The protein acts as a cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Entrez Gene ID
UniProt ID
Alternative Names
Tslp; thymic stromal lymphopoietin; TSLP; thymic stromal lymphopoietin
Function
Isoform 1
Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Isoform 2
May act as an antimicrobial peptide in the oral cavity and on the skin.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide Source:UniProtKB
Biological Process defense response to fungus Source:UniProtKB
Biological Process defense response to Gram-negative bacterium Source:UniProtKB
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of cell population proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of chemokine (C-C motif) ligand 1 production Source:UniProtKB1 Publication
Biological Process positive regulation of chemokine production Source:UniProtKB1 Publication
Biological Process positive regulation of cytokine-mediated signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of granulocyte colony-stimulating factor production Source:UniProtKB1 Publication
Biological Process positive regulation of inflammatory response Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-10 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-13 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-5 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-6 production Source:UniProtKB1 Publication
Biological Process positive regulation of mast cell activation Source:UniProtKB1 Publication
Biological Process positive regulation of receptor signaling pathway via STAT Source:UniProtKB1 Publication
Biological Process positive regulation of tyrosine phosphorylation of STAT protein Source:UniProtKB1 Publication
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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