Human Recombinant TSLP (R127A, R130S) protein, His Tag-1 (V2LY-0526-LY7440)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant TSLP (R127A, R130S) protein, His Tag consist of Amino Acid: 29-159 and predicts a molecular mass of 16.2 kDa.
Molecule Mass
16.2 kDa
Verified
HPLC
Sequence
Amino Acid: 29-159
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥90% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.
Endotoxin
<0.5 EU/mg protein.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
TSLP Gene(Protein Coding) Thymic Stromal Lymphopoietin
Function
Isoform 1
Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Isoform 2
May act as an antimicrobial peptide in the oral cavity and on the skin.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide Source:UniProtKB
Biological Process defense response to fungus Source:UniProtKB
Biological Process defense response to Gram-negative bacterium Source:UniProtKB
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of cell population proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of chemokine (C-C motif) ligand 1 production Source:UniProtKB1 Publication
Biological Process positive regulation of chemokine production Source:UniProtKB1 Publication
Biological Process positive regulation of cytokine-mediated signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of granulocyte colony-stimulating factor production Source:UniProtKB1 Publication
Biological Process positive regulation of inflammatory response Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-10 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-13 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-5 production Source:UniProtKB1 Publication
Biological Process positive regulation of interleukin-6 production Source:UniProtKB1 Publication
Biological Process positive regulation of mast cell activation Source:UniProtKB1 Publication
Biological Process positive regulation of receptor signaling pathway via STAT Source:UniProtKB1 Publication
Biological Process positive regulation of tyrosine phosphorylation of STAT protein Source:UniProtKB1 Publication
Cellular Location
Secreted
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Alternative Versions

Cynomolgus Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY1663)

Cynomolgus Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY1664)

Cynomolgus Recombinant TSLP protein, His Tag (CAT#: V2LY-0526-LY1665)

Human Recombinant TSLP protein, hFc Tag (CAT#: V2LY-0526-LY7433)

Human Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY7434)

Human Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY7435)

Human Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag-2 (CAT#: V2LY-0526-LY7436)

Human Recombinant TSLP protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY7437)

Human Recombinant TSLP protein, His Tag (CAT#: V2LY-0526-LY7438)

Human Recombinant TSLP (R127A, R130S) protein, His Tag (CAT#: V2LY-0526-LY7439)

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Cynomolgus Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY1664)

Human Recombinant TSLP protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY7435)

Human Recombinant TSLP protein, hFc Tag (CAT#: V2LY-0526-LY7433)

Rabbit Anti-TSLP Recombinant Antibody (D7U1X) (CAT#: CBMAB-CP2881-LY)

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Rhesus Recombinant TSLP protein, His Tag (CAT#: V2LY-0526-LY9801)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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