Mouse Anti-TSSK1B Recombinant Antibody (CBYJT-5097) (CBMAB-T4675-YJ)

Name: Mouse Anti-TSSK1B Recombinant Antibody (CBYJT-5097)
SKU: CBMAB-T4675-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5097

Application

ELISA, IF, WB

Immunogen

Partial recombinant corresponding to aa267-367 from human TSSK1 (AAH22515) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human, Mouse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 267-367

More Infomation

Target

Full Name

testis-specific serine kinase 1B

Introduction

TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).

Entrez Gene ID

83942

UniProt ID

Q9BXA7

Alternative Names

Testis Specific Serine Kinase 1B; Serine/Threonine Kinase 22D (Spermiogenesis Associated); Serine/Threonine-Protein Kinase 22A; Testis-Specific Serine Kinase 1; Testis-Specific Kinase 1; EC 2.7.11.1; STK22D; SPOGA4; TSSK-1; TSSK1; TSK-1

Function

Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.

Biological Process

Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process spermatid development Source:UniProtKB

Cellular Location

Cytoplasm
Cytoplasmic vesicle, secretory vesicle, acrosome
Cell projection, cilium, flagellum
In spermatozoa, present in the sperm head and in the flagellum.

PTM

Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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