TSSK1B

TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM

Full Name

testis-specific serine kinase 1B

Function

Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.

Biological Process

Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process spermatid development Source:UniProtKB

Cellular Location

Cytoplasm
Cytoplasmic vesicle, secretory vesicle, acrosome
Cell projection, cilium, flagellum
In spermatozoa, present in the sperm head and in the flagellum.

PTM

Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.

Anti-TSSK1B antibodies

Mouse Anti-TSSK1B Recombinant Antibody (2E8) (CBMAB-A9589-LY)

Datasheet

SDS

Target: TSSK1B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2E8

Application*: WB, E

Mouse Anti-TSSK1B Recombinant Antibody (4F12) (CBMAB-A9590-LY)

Datasheet

SDS

Target: TSSK1B

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse

Clone: 4F12

Application*: WB, E

Mouse Anti-TSSK1B Recombinant Antibody (CBYJT-5097) (CBMAB-T4675-YJ)

Datasheet

SDS

Target: TSSK1B

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBYJT-5097

Application*: E, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)