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Mouse Anti-TSSK6 Recombinant Antibody (6F5) (CBMAB-A9598-LY)

The product is antibody recognizes TSSK6. The antibody 6F5 immunoassay techniques such as: WB, ELISA.
See all TSSK6 antibodies
Published Data
Fig.1 Analysis of Tssks in mouse testis and in purified spermatogenic cells.
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Fig.2 Analysis of mouse Tssks tissue expression by western blotting.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
6F5
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TSSK6 (AAH14611, 174 a.a. ~ 273 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
testis-specific serine kinase 6
Introduction
TSSK6 is a serine/threonine protein kinase that is required for postmeiotic chromatin remodeling and male fertility (Spiridonov et al., 2005 [PubMed 15870294]).[supplied by OMIM
Entrez Gene ID
83983
UniProt ID
Q9BXA6
Alternative Names
FLJ24002; SSTK; TSSK4
Function
Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity).
Biological Process
Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process sperm DNA condensation Source:UniProtKB
Cellular Location
Nucleus
PTM
Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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