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Mouse Anti-TSSK6 Recombinant Antibody (CBYJT-5108) (CBMAB-T4686-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSSK6 (Testis Specific Serine Kinase 6). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TSSK6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5108
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa174-274 from human TSSK6 (AAH14611) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 174-274

Target

Full Name
testis-specific serine kinase 6
Introduction
TSSK6 is a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. TSSK6 has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm.
Entrez Gene ID
UniProt ID
Alternative Names
Testis Specific Serine Kinase 6; Cancer/Testis Antigen 72; Small Serine/Threonine Kinase; TSK-6; CT72; SSTK; Testis-Specific Serine/Threonine-Protein Kinase 6; Testis Secretory Sperm-Binding Protein Li 205a
Function
Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity).
Biological Process
Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process sperm DNA condensation Source:UniProtKB
Cellular Location
Nucleus
PTM
Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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