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Mouse Anti-TSSK6 Recombinant Antibody (CBYJT-5109) (CBMAB-T4687-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSSK6 (Testis Specific Serine Kinase 6). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TSSK6 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-5109
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Specific for an epitope mapping between amino acids 243-265 near the C-terminus of TSSK 6 of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 243-265

Target

Full Name
testis-specific serine kinase 6
Introduction
TSSK6 is a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. TSSK6 has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm.
Entrez Gene ID
Human83983
Mouse83984
Rat290670
UniProt ID
HumanQ9BXA6
MouseQ925K9
RatD3ZEK4
Alternative Names
Testis Specific Serine Kinase 6; Cancer/Testis Antigen 72; Small Serine/Threonine Kinase; TSK-6; CT72; SSTK; Testis-Specific Serine/Threonine-Protein Kinase 6; Testis Secretory Sperm-Binding Protein Li 205a
Function
Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity).
Biological Process
Biological Process intracellular signal transduction Source:GO_Central1 Publication
Biological Process peptidyl-serine phosphorylation Source:Ensembl
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process sperm DNA condensation Source:UniProtKB
Cellular Location
Nucleus
PTM
Autophosphorylated.
Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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