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Mouse Anti-TSTA3 Recombinant Antibody (2B9) (CBMAB-A9599-LY)

The product is antibody recognizes TSTA3. The antibody 2B9 immunoassay techniques such as: WB, ELISA.
See all TSTA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B9
Antibody Isotype
IgG3, κ
Application
WB, ELISA

Basic Information

Immunogen
TSTA3 (NP_003304, 222 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
tissue specific transplantation antigen P35B
Introduction
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq]
Entrez Gene ID
7264
UniProt ID
Q13630
Alternative Names
FX; P35B; SDR4E1
Function
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Biological Process
Biological Process 'de novo' GDP-L-fucose biosynthetic process Source:UniProtKB1 Publication
Biological Process GDP-mannose metabolic process Source:UniProtKB1 Publication
Biological Process leukocyte cell-cell adhesion Source:UniProtKB1 Publication
Biological Process positive regulation of endothelial cell migration Source:UniProtKB1 Publication
Biological Process positive regulation of endothelial cell-matrix adhesion via fibronectin Source:UniProtKB1 Publication
Cellular Location
cytosol
extracellular exosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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