Rabbit Anti-TTF1 Recombinant Antibody (D2E8) (CBMAB-CP2760-LY)

Name: Rabbit Anti-TTF1 Recombinant Antibody (D2E8)
SKU: CBMAB-CP2760-LY
Rating: 5 (1 reviews)

See all TTF1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

D2E8

Application

WB, IF, IF (ICC)

Immunogen

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human thyroid transcription factor 1 protein.

Specificity

Human, Mouse, Rat, Monkey

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

100 µg/ml BSA, 50% glycerol

Preservative

0.02% sodium azide

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TTF1 Transcription Termination Factor 1

Introduction

This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011]

Entrez Gene ID

Human	7270
Mouse	22130
Rat	499766
Monkey	715002

UniProt ID

Human	Q15361
Mouse	Q62187
Rat	D4A1Z7
Monkey	F6WZZ6

Alternative Names

Transcription Termination Factor 1; Transcription Termination Factor; RNA Polymerase I; TTF-1; TTF-I; RNA Polymerase I Termination Factor; Transcription Termination Factor I;

Function

Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.

Biological Process

DNA-templated transcription, termination1 PublicationNAS:UniProtKB
Negative regulation of DNA replicationIEA:UniProtKB-KW
Termination of RNA polymerase I transcriptionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus
Nucleus, nucleolus

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-TTF1 Recombinant Antibody (D2E8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TTF1 Recombinant Antibody (CF457) (CAT#: CBMAB-FT069LY)

Mouse Anti-TTF1 Recombinant Antibody (CBYJT-5144) (CAT#: CBMAB-T4722-YJ)

Mouse Anti-TTF1 Recombinant Antibody (CBT4036) (CAT#: V2LY-0625-LY473)

Mouse Anti-TTF1 Recombinant Antibody (CBYJT-5145) (CAT#: CBMAB-T4723-YJ)

Mouse Anti-TTF1 Recombinant Antibody (CBYJT-5146) (CAT#: CBMAB-T4724-YJ)

Mouse Anti-TTF1 Recombinant Antibody (IHC414) (CAT#: CBMAB-MA255-YC)

Mouse Anti-TTF1 Recombinant Antibody (CBT4345) (CAT#: V2LY-0625-LY472)

Rabbit Anti-TTF1 Monoclonal Antibody (SP141) (CAT#: CBMAB-R0083-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry