Mouse Anti-TUBB1 Recombinant Antibody (
8H4) (V2LY-0725-LY86)
Compare
Online Inquiry
Basic Information
| Application | Note |
| WB | 1:500-1:5,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process mitotic cell cycle Source:GO_Central1 Publication
Biological Process spindle assembly Source:Ensembl
A congenital blood disorder characterized by increased platelet size and decreased number of circulating platelets.
Polyglutamylation plays a key role in microtubule severing by spastin (SPAST). SPAST preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity by SPAST increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold (PubMed:26875866).
Glutamylation is also involved in cilia motility (By similarity).
Some glutamate residues at the C-terminus are monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into cilia and flagella axonemes, which is required for their stability and maintenance. Flagella glycylation controls sperm motility. Both polyglutamylation and monoglycylation can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally.
Phosphorylated on Ser-172 by CDK1 during the cell cycle, from metaphase to telophase, but not in interphase. This phosphorylation inhibits tubulin incorporation into microtubules.
8H4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5287) (CAT#: CBMAB-T4877-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5283) (CAT#: CBMAB-T4873-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (600C2a) (CAT#: CBMAB-T4878-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (CB376) (CAT#: CBMAB-CS376LY)
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5289) (CAT#: CBMAB-T4880-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5286) (CAT#: CBMAB-T4876-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5290) (CAT#: CBMAB-T4882-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (CBYJT-5285) (CAT#: CBMAB-T4875-YJ)
Mouse Anti-TUBB1 Recombinant Antibody (
15E10) (CAT#: V2LY-0725-LY499)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
