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Mouse Anti-UBASH3A Recombinant Antibody (1G6) (CBMAB-A9695-LY)

The product is antibody recognizes UBASH3A. The antibody 1G6 immunoassay techniques such as: WB, ELISA.
See all UBASH3A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
UBASH3A (NP_001001895, 524 a.a. ~ 623 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ubiquitin associated and SH3 domain containing, A
Entrez Gene ID
53347
UniProt ID
P57075
Alternative Names
CLIP4; STS-2; TULA
Function
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Biological Process
Biological Process negative regulation of T cell receptor signaling pathway Source:GO_Central1 Publication
Biological Process regulation of cytokine production Source:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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