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Mouse Anti-UBE2E2 Antibody (12BA19) (CBMAB-1740CQ)

This product is a mouse antibody that recognizes UBE2E2. The antibody 12BA19 can be used for immunoassay techniques such as: ELISA, WB.
See all UBE2E2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
12BA19
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
Recombinant full length protein
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
UBE2E2
Introduction
UBE2E2 (Ubiquitin Conjugating Enzyme E2 E2) accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-11- and Lys-48-, as well as Lys-63-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. GO annotations related to this gene include ligase activity and acid-amino acid ligase activity.
Entrez Gene ID
7325
UniProt ID
Q96LR5
Alternative Names
Ubiquitin-Conjugating Enzyme E2E 2; Yeast UBC4/5; Ubiquitin-Conjugating Enzyme E2E 2; UbcH8; Ubiquitin Carrier Protein E2; Ubiquitin-Protein Ligase E2; UBCH8; EC 6.3.2.19; FLJ25157;
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.
Biological Process
Biological Process cellular response to DNA damage stimulus Source:MGI1 Publication
Biological Process ISG15-protein conjugation Source:HGNC-UCL1 Publication
Biological Process positive regulation of G1/S transition of mitotic cell cycle Source:MGI1 Publication
Biological Process protein K11-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein K48-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein K63-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Autoubiquitinated in vitro.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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