UBE2E2

UBE2E2 (Ubiquitin Conjugating Enzyme E2 E2) accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-11- and Lys-48-, as well as Lys-63-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. GO annotations related to this gene include ligase activity and acid-amino acid ligase activity.
Full Name
UBE2E2
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.
Biological Process
Biological Process cellular response to DNA damage stimulus Source:MGI1 Publication
Biological Process ISG15-protein conjugation Source:HGNC-UCL1 Publication
Biological Process positive regulation of G1/S transition of mitotic cell cycle Source:MGI1 Publication
Biological Process protein K11-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein K48-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein K63-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Autoubiquitinated in vitro.
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Anti-UBE2E2 antibodies

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Mouse Anti-UBE2E2 Antibody (12BA21) (CBMAB-1742CQ)

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Target: UBE2E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12BA21
Application*: E, WB
Datasheet SDS

Mouse Anti-UBE2E2 Antibody (12BA20) (CBMAB-1741CQ)

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Target: UBE2E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12BA20
Application*: E, WB
Datasheet SDS

Mouse Anti-UBE2E2 Antibody (12BA19) (CBMAB-1740CQ)

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Target: UBE2E2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 12BA19
Application*: E, WB
Datasheet SDS

Mouse Anti-UBE2E2 Recombinant Antibody (4B4) (CBMAB-A9709-LY)

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Target: UBE2E2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4B4
Application*: WB, E
Datasheet SDS

Rabbit Anti-UBE2E2 Recombinant Antibody (CBFYU-101) (CBMAB-U0101-FY)

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Target: UBE2E2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBFYU-101
Application*: WB, P
Datasheet SDS

Mouse Anti-UBE2E2 Recombinant Antibody (CBFYU-098) (CBMAB-U0098-FY)

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Target: UBE2E2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYU-098
Application*: E, IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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