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Mouse Anti-UBQLN2 Monoclonal Antibody (1C7) (CBMAB-0285-LY)

This product is mouse monoclonal antibody recognizes UBQLN2 of human. The antibody 1C7 immunoassay techniques such as: IP, MA, WB.
Host Species
Mouse
Application
IP, MA, WB
Immunogen
Recombinant peptide (Protein Domain)
Antibody Isotype
IgG1
Specificity
Human
Clone
1C7
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome.
Alternative Name
Chap1; CHAP1/DSK2; Dsk2; LIC-2; N4BP4; PLIC-2; PLIC2; RIHFB2157
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0285-LY
Conjugates
Size
Price $
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Second antibody and isotype control