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Mouse Anti-UCK1 Recombinant Antibody (1A12) (CBMAB-C4475-CN)

This product is a Mouse antibody that recognizes UCK1. The antibody 1A12 can be used for immunoassay techniques such as: WB, FC, IF.
See all UCK1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A12
Antibody Isotype
IgG1
Application
WB, FC, IF

Basic Information

Immunogen
Full length human recombinant protein of human UCK1 (NP_113620) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Uridine-Cytidine Kinase 1
Introduction
This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]
Entrez Gene ID
UniProt ID
Alternative Names
Uridine-Cytidine Kinase 1; Cytidine Monophosphokinase 1; Uridine Monophosphokinase 1; EC 2.7.1.48; URK1; UCK 1;
Function
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702).
Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702).
Can use ATP or GTP as a phosphate donor (PubMed:11306702).
Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N4-acetylcytidine, N4-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N4-anisoylcytidine (PubMed:11306702).
Biological Process
Biological Process CTP salvage Source:UniProtKB1 Publication
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process UMP salvage Source:UniProtKB1 Publication
Cellular Location
cytoplasm
cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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