Mouse Anti-UCK1 Recombinant Antibody (7E11) (CBMAB-C4483-CN)

Name: Mouse Anti-UCK1 Recombinant Antibody (7E11)
SKU: CBMAB-C4483-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

7E11

Application

Immunogen

Full length human recombinant protein of human UCK1 (NP_113620) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% Sodium azide

More Infomation

Target

Full Name

Uridine-Cytidine Kinase 1

Introduction

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]

Entrez Gene ID

83549

UniProt ID

Q9HA47

Alternative Names

Uridine-Cytidine Kinase 1; Cytidine Monophosphokinase 1; Uridine Monophosphokinase 1; EC 2.7.1.48; URK1; UCK 1;

Function

Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702).
Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702).
Can use ATP or GTP as a phosphate donor (PubMed:11306702).
Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N4-acetylcytidine, N4-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N4-anisoylcytidine (PubMed:11306702).

Biological Process

Biological Process CTP salvage Source:UniProtKB1 Publication
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process UMP salvage Source:UniProtKB1 Publication

Cellular Location

cytoplasm
cytosol

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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