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UCK1

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]
Full Name
Uridine-Cytidine Kinase 1
Function
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702).
Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702).
Can use ATP or GTP as a phosphate donor (PubMed:11306702).
Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N4-acetylcytidine, N4-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N4-anisoylcytidine (PubMed:11306702).
Biological Process
Biological Process CTP salvage Source:UniProtKB1 Publication
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process UMP salvage Source:UniProtKB1 Publication
Cellular Location
cytoplasm
cytosol
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Anti-UCK1 antibodies

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Mouse Anti-UCK1 Recombinant Antibody (7E11) (CBMAB-C4483-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E11
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (6H7) (CBMAB-C4482-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6H7
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (6E12) (CBMAB-C4481-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6E12
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (6B6) (CBMAB-C4480-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B6
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (5E9) (CBMAB-C4479-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E9
Application*: FC, IF, WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (4H1) (CBMAB-C4478-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4H1
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (4C2) (CBMAB-C4477-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4C2
Application*: IF, WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (2E8) (CBMAB-C4476-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2E8
Application*: WB
Datasheet SDS

Mouse Anti-UCK1 Recombinant Antibody (1A12) (CBMAB-C4475-CN)

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Target: UCK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A12
Application*: WB, FC, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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