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Mouse Anti-UCN3 Recombinant Antibody (13j95) (CBMAB-C4498-CN)

This product is a Mouse antibody that recognizes UCN3. The antibody 13j95 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all UCN3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
13j95
Application
ELISA, IF, IHC, WB

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 50% glycerol
Preservative
0.05% Sodium azide
Concentration
0.5 mg/mL

Target

Full Name
Urocortin 3
Introduction
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016]
Entrez Gene ID
114131
UniProt ID
Q969E3
Alternative Names
Urocortin 3; Stresscopin; Prepro-Urocortin 3; Urocortin III; Ucn III; SPC; Urocortin-3; UCNIII; SCP;
Function
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway Source:UniProtKB1 Publication
Biological Process cellular response to hypoxia Source:Ensembl
Biological Process cellular response to nutrient levels Source:GO_Central1 Publication
Biological Process digestion Source:InterPro
Biological Process hormone-mediated signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of insulin secretion Source:Ensembl
Biological Process positive regulation of membrane potential Source:Ensembl
Biological Process response to corticosterone Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to immobilization stress Source:Ensembl
Biological Process response to starvation Source:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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