Mouse Anti-UCN3 Recombinant Antibody (CBXS-0936) (CBMAB-S3850-CQ)

Name: Mouse Anti-UCN3 Recombinant Antibody (CBXS-0936)
SKU: CBMAB-S3850-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-0936

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Immunogen

Urocortin 3

Specificity

Rat

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.02% sodium azide

Concentration

0.5 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Urocortin 3

Introduction

This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.

Entrez Gene ID

498791

UniProt ID

A1YKY5

Alternative Names

RGD1562213

Function

Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

Biological Process

Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway Source:UniProtKB1 Publication
Biological Process cellular response to hypoxia Source:Ensembl
Biological Process cellular response to nutrient levels Source:GO_Central1 Publication
Biological Process digestion Source:InterPro
Biological Process hormone-mediated signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of insulin secretion Source:Ensembl
Biological Process positive regulation of membrane potential Source:Ensembl
Biological Process response to corticosterone Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to immobilization stress Source:Ensembl
Biological Process response to starvation Source:Ensembl

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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