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Mouse Anti-UCP3 Recombinant Antibody (CBT3262) (V2LY-0625-LY503)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT3262
Antibody Isotype
IgG2a
Application
ICC

Basic Information

Immunogen
Purified recombinant fragment of human UCP3 (AA: 1-113 and 217-312) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ICC1:200-1:1,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Uncoupling Protein 3
Entrez Gene ID
7352
Function
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
Biological Process
Biological Process adaptive thermogenesis Source:GO_Central1 Publication
Biological Process aging Source:Ensembl
Biological Process cellular response to hormone stimulus Source:Ensembl
Biological Process fatty acid metabolic process Source:Ensembl
Biological Process lipid metabolic process Source:ProtInc1 Publication
Biological Process mitochondrial transmembrane transport Source:GO_Central1 Publication
Biological Process mitochondrial transport Source:InterPro
Biological Process proton transmembrane transport Source:ProtInc1 Publication
Biological Process respiratory gaseous exchange by respiratory system Source:ProtInc1 Publication
Biological Process response to activity Source:Ensembl
Biological Process response to cold Source:GO_Central1 Publication
Biological Process response to glucocorticoid Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to insulin Source:Ensembl
Biological Process response to nutrient Source:Ensembl
Biological Process response to superoxide Source:Ensembl
Cellular Location
Mitochondrion inner membrane
Involvement in disease
Obesity (OBESITY):
A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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