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Mouse Anti-UCP3 Recombinant Antibody (mAb61299) (CBMAB-0924CQ)

This product is a mouse antibody that recognizes UCP3. The antibody mAb61299 can be used for immunoassay techniques such as: WB.
See all UCP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
mAb61299
Antibody Isotype
IgM
Application
WB

Basic Information

Immunogen
Human UCP3 aa 100-200
Specificity
Human
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Uncoupling Protein 3
Introduction
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
Entrez Gene ID
7352
UniProt ID
P55916
Alternative Names
SLC25A9
Function
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
Biological Process
Biological Process adaptive thermogenesis Source:GO_Central1 Publication
Biological Process aging Source:Ensembl
Biological Process cellular response to hormone stimulus Source:Ensembl
Biological Process fatty acid metabolic process Source:Ensembl
Biological Process lipid metabolic process Source:ProtInc1 Publication
Biological Process mitochondrial transmembrane transport Source:GO_Central1 Publication
Biological Process mitochondrial transport Source:InterPro
Biological Process proton transmembrane transport Source:ProtInc1 Publication
Biological Process respiratory gaseous exchange by respiratory system Source:ProtInc1 Publication
Biological Process response to activity Source:Ensembl
Biological Process response to cold Source:GO_Central1 Publication
Biological Process response to glucocorticoid Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to insulin Source:Ensembl
Biological Process response to nutrient Source:Ensembl
Biological Process response to superoxide Source:Ensembl
Cellular Location
Mitochondrion inner membrane
Involvement in disease
Obesity (OBESITY):
A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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