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Recombinant Mouse Anti-USP3 Recombinant Antibody (AE9-12-1) (CBMAB-XB1209-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
AE9-12-1
Application
IP, WB

Basic Information

Specificity
Human, Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ubiquitin specific peptidase 3
Introduction
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
Entrez Gene ID
Human9960
Mouse235441
UniProt ID
HumanQ9Y6I4
MouseQ91W36
Alternative Names
Ubiquitin Specific Peptidase 3; Ubiquitin-Specific-Processing Protease 3; Deubiquitinating Enzyme 3; Ubiquitin Thioesterase 3; Ubiquitin Carboxyl-Terminal Hydrolase 3; Ubiquitin Specific Protease 3;
Function
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
Biological Process
Biological Process chromatin organization Source:UniProtKB-KW
Biological Process DNA repair Source:UniProtKB1 Publication
Biological Process histone deubiquitination Source:UniProtKB1 Publication
Biological Process mitotic cell cycle Source:UniProtKB1 Publication
Biological Process regulation of protein stability Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro
Cellular Location
Nucleus
Localizes preferentially with monoubiquitinated H2A to chromatin.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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