Mouse Anti-USP46 Recombinant Antibody (CBXU-164) (CBMAB-U0232-CQ)

Name: Mouse Anti-USP46 Recombinant Antibody (CBXU-164)
SKU: CBMAB-U0232-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXU-164

Application

Immunogen

Recombinant protein corresponding to human USP46

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 40% glycerol

Preservative

0.02% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Ubiquitin Specific Peptidase 46

Introduction

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes.

Entrez Gene ID

64854

UniProt ID

P62068

Alternative Names

USP46; ubiquitin specific peptidase 46; ubiquitin specific protease 46; ubiquitin carboxyl-terminal hydrolase 46; FLJ12552; ubiquitin thioesterase 46; deubiquitinating enzyme 46; ubiquitin thiolesterase 46; ubiquitin-specific-processing protease 46

Function

Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity).
Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029).
Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).

Biological Process

Biological Process adult feeding behavior Source:Ensembl
Biological Process behavioral fear response Source:Ensembl
Biological Process behavioral response to ethanol Source:Ensembl
Biological Process protein deubiquitination Source:UniProtKB1 Publication
Biological Process regulation of synaptic transmission, GABAergic Source:UniProtKB
Biological Process righting reflex Source:Ensembl
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro

Cellular Location

cytosol
nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-USP46 Recombinant Antibody (CBXU-165) (CAT#: CBMAB-U0233-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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