Human Recombinant USP46 protein, His Tag (V2LY-0526-LY7570)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant USP46 protein, His Tag consist of Amino Acid: Full Length and predicts a molecular mass of 44 kDa.
Molecule Mass
44 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
Ubiquitin Specific Peptidase 46
Function
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity).
Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029).
Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).
Biological Process
Biological Process adult feeding behavior Source:Ensembl
Biological Process behavioral fear response Source:Ensembl
Biological Process behavioral response to ethanol Source:Ensembl
Biological Process protein deubiquitination Source:UniProtKB1 Publication
Biological Process regulation of synaptic transmission, GABAergic Source:UniProtKB
Biological Process righting reflex Source:Ensembl
Biological Process ubiquitin-dependent protein catabolic process Source:InterPro
Cellular Location
cytosol
nucleus
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For research use only. Not intended for any clinical use.

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