Mouse Anti-VAMP5 Recombinant Antibody (CBYY-1760) (CBMAB-1261-YY)

Name: Mouse Anti-VAMP5 Recombinant Antibody (CBYY-1760)
SKU: CBMAB-1261-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYY-1760

Application

WB, IHC

Immunogen

GST-mV5-II and KLH-mV5-II peptide sequences

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1.0 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

vesicle-associated membrane protein 5 (myobrevin)

Introduction

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily.

Entrez Gene ID

10791

UniProt ID

O95183

Alternative Names

Vascular Endothelium Marker

Function

May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process Golgi to plasma membrane protein transport Source:GO_Central1 Publication
Biological Process muscle organ development Source:ProtInc1 Publication
Biological Process skeletal muscle tissue development Source:Ensembl

Cellular Location

Cell membrane
Endomembrane system
Golgi apparatus, trans-Golgi network membrane
Associated with the plasma membrane as well as intracellular perinuclear and peripheral vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi apparatus (By similarity).

Topology

Cytoplasmic: 1-72
Helical: 73-93
Vesicular: 94-116

PTM

(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type X (BoNT/X) which hydrolyzes the 40-Arg-|-Ser-41 bond and probably inhibits neurotransmitter release (PubMed:28770820).
It remains unknown whether BoNT/X is ever produced, or what organisms it targets.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-VAMP5 Recombinant Antibody (3D4) (CAT#: CBMAB-A9851-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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