Mouse Anti-VAV2 Recombinant Antibody (CBT2272) (V2LY-0625-LY248)

Name: Mouse Anti-VAV2 Recombinant Antibody (CBT2272)
SKU: V2LY-0625-LY248
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-VAV2 Recombinant Antibody (CBT2272) (V2LY-0625-LY248) in ELISA

Mouse Anti-VAV2 Recombinant Antibody (CBT2272) (V2LY-0625-LY248) in WB

Mouse Anti-VAV2 Recombinant Antibody (CBT2272) (V2LY-0625-LY248) in FC

Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBT2272

Application

Immunogen

Purified recombinant fragment of human VAV2 (AA: 552-868) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

VAV2

Entrez Gene ID

7410

Function

Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).

Biological Process

Biological Process angiogenesis Source:UniProtKB-KW
Biological Process cell migration Source:GO_Central1 Publication
Biological Process cellular response to xenobiotic stimulus Source:Reactome
Biological Process Fc-epsilon receptor signaling pathway Source:Reactome
Biological Process Fc-gamma receptor signaling pathway involved in phagocytosis Source:Reactome
Biological Process lamellipodium assembly Source:Ensembl
Biological Process platelet activation Source:Reactome
Biological Process positive regulation of phosphatidylinositol 3-kinase activity Source:Ensembl
Biological Process regulation of cell size Source:UniProtKB1 Publication
Biological Process regulation of GTPase activity Source:UniProtKB1 Publication
Biological Process regulation of small GTPase mediated signal transduction Source:Reactome
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process small GTPase mediated signal transduction Source:Ensembl
Biological Process vascular endothelial growth factor receptor signaling pathway Source:Reactome

Cellular Location

cytoplasm
cytosol
plasma membrane

PTM

Phosphorylated on tyrosine residues in response to FGR activation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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