Human Anti-VSIG4 Recombinant Antibody (
12D12) (V2LY-0725-LY1441)

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Tested Data
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Basic Information

Host Animal
Human
Clone
12D12
Application
ELISA
Immunogen
Recombinant Human VSIG4 protein.
Host Species
Human
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, Glycerol
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
V-Set And Immunoglobulin Domain Containing 4
Entrez Gene ID
UniProt ID
Function
Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
Biological Process
Biological Process complement activation, alternative pathway Source:UniProtKB-KW
Biological Process negative regulation of complement activation, alternative pathway Source:UniProtKB1 Publication
Biological Process negative regulation of interleukin-2 production Source:GO_Central1 Publication
Biological Process negative regulation of macrophage activation Source:InterPro
Biological Process negative regulation of T cell proliferation Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 20-283
Helical: 284-304
Cytoplasmic: 305-399
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12D12)?

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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