Rat Anti-VSIG4 Recombinant Antibody (NLA14) (CBMAB-V0004-YC)

Name: Rat Anti-VSIG4 Recombinant Antibody (NLA14)
SKU: CBMAB-V0004-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

NLA14

Application

Specificity

Mouse

Antibody Isotype

IgG2a, к

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

V-Set And Immunoglobulin Domain Containing 4

Introduction

VSIG4 is a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins.

Entrez Gene ID

278180

UniProt ID

F6TUL9

Alternative Names

V-Set And Immunoglobulin Domain Containing 4; Protein Z39Ig; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Ig Superfamily Protein

Function

Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.

Biological Process

Biological Process complement activation, alternative pathway Source:UniProtKB-KW
Biological Process negative regulation of complement activation, alternative pathway Source:UniProtKB1 Publication
Biological Process negative regulation of interleukin-2 production Source:GO_Central1 Publication
Biological Process negative regulation of macrophage activation Source:InterPro
Biological Process negative regulation of T cell proliferation Source:GO_Central1 Publication

Cellular Location

Membrane

Topology

Extracellular: 20-283
Helical: 284-304
Cytoplasmic: 305-399

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-VSIG4 Recombinant Antibody (3) (CAT#: CBMAB-V0071-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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