Sign in or Register   Sign in or Register
  |  

Mouse Anti-WSB1 Recombinant Antibody (3E10) (CBMAB-W0095-WJ)

This product is a mouse antibody that recognizes WSB1. The antibody 3E10 can be used for immunoassay techniques such as: ELISA.
See all WSB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3E10
Antibody Isotype
IgG2a, к
Application
ELISA

Basic Information

Immunogen
WSB1 (AAH21110.1, aa53-137) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: QGHRTVKLVP WSQCLQNFLL HGTKNVTNSS SLRLPRQNSD GGQKNKPREH IIDCGDIVWS LAFGSSVPEK QSRCVNIEWH RFRFG
Specificity
Human
Antibody Isotype
IgG2a, к
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD repeat and SOCS box-containing 1
Introduction
WSB1 is a protein-coding gene encodes a member of the WD-protein subfamily. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is WSB2.
Entrez Gene ID
26118
UniProt ID
Q9Y6I7
Alternative Names
SWIP1; WSB-1
Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
Biological Process
Biological Process intracellular signal transduction Source:InterPro
Biological Process protein aggregate center assembly Source:Ensembl
Biological Process protein K27-linked ubiquitination Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Cellular Location
cytosol
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-WSB1 Recombinant Antibody (3E10)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare