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Recombinant Mouse Anti-WSB1 Recombinant Antibody (K5P2H10) (CBMAB-XB1231-YC)

Provided herein is a Mouse Recombinant Antibody against WD Repeat And SOCS Box Containing 1. The antibody can be used for immunoassay techniques, such as ELISA, IHC, WB.
See all WSB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
K5P2H10
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Ovalbumin-conjugated Synthetic peptide RRVMPTQEVQE
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD repeat and SOCS box-containing 1
Introduction
WSB1 is a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Entrez Gene ID
26118
UniProt ID
Q9Y6I7
Alternative Names
WD Repeat And SOCS Box Containing 1; SOCS Box-Containing WD Protein SWiP-1; SWIP1; WSB-1; WD Repeat And SOCS Box-Containing Protein 1; WD Repeat And SOCS Box-Containing 1;
Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
Biological Process
Biological Process intracellular signal transduction Source:InterPro
Biological Process protein aggregate center assembly Source:Ensembl
Biological Process protein K27-linked ubiquitination Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Cellular Location
cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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