WSB1

This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Full Name
WD repeat and SOCS box-containing 1
Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
Biological Process
Biological Process intracellular signal transduction Source:InterPro
Biological Process protein aggregate center assembly Source:Ensembl
Biological Process protein K27-linked ubiquitination Source:Ensembl
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Cellular Location
cytosol
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Anti-WSB1 antibodies

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Recombinant Mouse Anti-WSB1 Recombinant Antibody (K5P2H10) (CBMAB-XB1231-YC)

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Target: WSB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: K5P2H10
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-WSB1 Recombinant Antibody (K5P6A5) (CBMAB-W0331-WJ)

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Target: WSB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: K5P6A5
Application*: WB, E, IH
Datasheet SDS

Mouse Anti-WSB1 Recombinant Antibody (3E10) (CBMAB-W0095-WJ)

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Target: WSB1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3E10
Application*: E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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