Mouse Anti-ZNRF4 Recombinant Antibody (CBWJZ-103) (CBMAB-Z0697-WJ)

Name: Mouse Anti-ZNRF4 Recombinant Antibody (CBWJZ-103)
SKU: CBMAB-Z0697-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBWJZ-103

Application

S-ELISA, ELISA, WB

Immunogen

ZNRF4 (AA108-170) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

More Infomation

Target

Full Name

zinc and ring finger 4

Introduction

ZNRF4 (Zinc And Ring Finger 4) is a Protein Coding gene. Diseases associated with ZNRF4 include Deafness, Autosomal Recessive 68 and Deafness, Autosomal Recessive 15. An important paralog of this gene is RNF13.

Entrez Gene ID

148066

UniProt ID

Q8WWF5

Alternative Names

spzn; RNF204; Ssrzf1; SPERIZIN

Function

E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2 (PubMed:28656966).
Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830).
Could have a role in spermatogenesis (By similarity).

Biological Process

Biological Process ubiquitin-dependent protein catabolic process Source:UniProtKB1 Publication

Cellular Location

Endoplasmic reticulum membrane

Topology

Lumenal: 28-250
Helical: 251-271
Cytoplasmic: 272-429

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-ZNRF4 Recombinant Antibody (1A8) (CAT#: CBMAB-Z0698-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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