Mouse Anti-ZWINT Recombinant Antibody (1B7) (CBMAB-Z0797-WJ)

Name: Mouse Anti-ZWINT Recombinant Antibody (1B7)
SKU: CBMAB-Z0797-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1B7

Application

ELISA, WB

Immunogen

ZWINT (AA1-278) full-length recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

More Infomation

Target

Full Name

ZW10 Interacting Kinetochore Protein

Introduction

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

11130

UniProt ID

O95229

Alternative Names

SIP30; ZWINT1; KNTC2AP; HZwint-1

Function

Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.

Biological Process

Biological Process cell division Source:UniProtKB-KW
Biological Process establishment of localization in cell Source:HGNC-UCL1 Publication
Biological Process mitotic sister chromatid segregation Source:HGNC-UCL1 Publication
Biological Process mitotic spindle assembly checkpoint signaling Source:HGNC-UCL1 Publication

Cellular Location

Nucleus
Chromosome, centromere, kinetochore
Note: Localizes to kinetochores from late prophase to anaphase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

ZWINT Matched Antibody Pair (1337) (CAT#: APMAB-1337LY)

Related Products

ZWINT Matched Antibody Pair (1337) (CAT#: APMAB-1337LY)

Mouse Anti-ZWINT Recombinant Antibody (6D3) (CAT#: CBMAB-Z0796-WJ)

Mouse Anti-ZWINT Recombinant Antibody (422CT4.6.4) (CAT#: CBMAB-Z0795-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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