ANXA5 Matched Antibody Pair (083) (APMAB-083LY)

Name: ANXA5 Matched Antibody Pair (083)
SKU: APMAB-083LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-ANXA5 polyclonal antibody, 100 ug

Detection Antibody

Anti-ANXA5 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008]

Alternative Names

Annexin A5; Placental Anticoagulant Protein 4; Placental Anticoagulant Protein I; Vascular Anticoagulant-Alpha; Thromboplastin Inhibitor; Calphobindin I; Anchorin CII; Endonexin II; Lipocortin V; Annexin V; Annexin-5;

Entrez Gene ID

308

UniProt ID

P08758

More Infomation

Haeckel, A., Ascher, L., Beindorff, N., Prasad, S., Garczyńska, K., Guo, J., & Schellenberger, E. (2021). Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications. Apoptosis, 1-14.

Dryllis, G., Giannopoulos, A., Zoi, C., Pouliakis, A., Logothetis, E., Voulgarelis, M., ... & Politou, M. (2020). Correlation of single nucleotide polymorphisms in the promoter region of the ANXA5 (annexin A5) gene with recurrent miscarriages in women of Greek origin. The Journal of Maternal-Fetal & Neonatal Medicine, 33(9), 1538-1543.

Bolean, M., Izzi, B., Bottini, M., Ramos, A. P., Millán, J. L., Hoylaerts, M. F., & Ciancaglini, P. (2020). Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells. Biochimica et Biophysica Acta (BBA)-General Subjects, 1864(8), 129629.

Terashima, R., Saigo, T., Laoharatchatathanin, T., Kurusu, S., Brachvogel, B., Pöschl, E., & Kawaminami, M. (2020). Augmentation of Nr4a3 and suppression of Fshb expression in the pituitary gland of female Annexin A5 null mouse. Journal of the Endocrine Society, 4(9), bvaa096.

Kang, T. H., Park, J. H., Yang, A., Park, H. J., Lee, S. E., Kim, Y. S., ... & Hung, C. F. (2020). Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment. Nature communications, 11(1), 1-16.

Yu, C., Muñoz, L. E., Mallavarapu, M., Herrmann, M., & Finnemann, S. C. (2019). Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis. Journal of cell science, 132(20), jcs232439.

Danisik, H., Bogdanova, N., & Markoff, A. (2019). Micromolar zinc in Annexin A5 anticoagulation as a potential remedy for RPRGL3-associated recurrent pregnancy loss. Reproductive Sciences, 26(3), 348-356.

de Jong, R. C., Pluijmert, N. J., de Vries, M. R., Pettersson, K., Atsma, D. E., Jukema, J. W., & Quax, P. H. (2018). Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response. Scientific reports, 8(1), 1-10.

Zhang, B., Zeng, X., Xu, Y., Zhang, Y., Huang, N., Gu, Y., ... & Liu, X. (2017). The association between annexin A5 (ANXA5) gene polymorphism and left ventricular hypertrophy (LVH) in Chinese endogenous hypertension patients. Medicine, 96(44).

Baek, H. S., Park, N., Kwon, Y. J., Ye, D. J., Shin, S., & Chun, Y. J. (2017). Annexin A5 suppresses cyclooxygenase-2 expression by downregulating the protein kinase C-ζ–nuclear factor-κB signaling pathway in prostate cancer cells. Oncotarget, 8(43), 74263.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human ANXA5 ELISA Kit (CAT#: V2LY-0626-LY1389)

Human ANXA5 ELISA Kit (2) (CAT#: V2LY-0626-LY3578)

Cattle ANXA5 ELISA Kit (CAT#: V2LY-0626-LY685)

Rat Anxa5 ELISA Kit (CAT#: V2LY-0626-LY895)

ANXA5 Matched Antibody Pair (082) (CAT#: APMAB-082LY)

Human Recombinant ANXA5 protein, His Tag (CAT#: V2LY-0526-LY2124)

Human Recombinant ANXA5 protein, Biotin Conjugated (CAT#: V2LY-0526-LY2125)

Human Recombinant ANXA5 protein (CAT#: V2LY-0526-LY2126)

Antibody Pairs

ANXA5 Matched Antibody Pair (082) (CAT#: APMAB-082LY)

Related Products

Mouse Anti-ANXA5 Recombinant Antibody (CBT3603) (CAT#: V2LY-0625-LY252)

Human ANXA5 ELISA Kit (2) (CAT#: V2LY-0626-LY3578)

Human ANXA5 ELISA Kit (CAT#: V2LY-0626-LY1389)

Mouse Anti-ANXA5 Recombinant Antibody (CBYC-A636) (CAT#: CBMAB-A2934-YC)

Mouse Anti-ANXA5 Recombinant Antibody (3B9F3) (CAT#: CBMAB-A2928-YC)

Rat Anxa5 ELISA Kit (CAT#: V2LY-0626-LY895)

ANXA5 Matched Antibody Pair (082) (CAT#: APMAB-082LY)

Human Recombinant ANXA5 protein, Biotin Conjugated (CAT#: V2LY-0526-LY2125)

Cattle ANXA5 ELISA Kit (CAT#: V2LY-0626-LY685)

Mouse Anti-ANXA5 Recombinant Antibody (CF030) (CAT#: CBMAB-FT458LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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