BAG5 Matched Antibody Pair (125) (APMAB-125LY)

Name: BAG5 Matched Antibody Pair (125)
SKU: APMAB-125LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-BAG5 monoclonal antibody, 100 ug

Detection Antibody

Anti-BAG5 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative Names

BCL2 Associated Athanogene 5; Bcl-2-Associated Athanogene 5; BAG-5; BAG Family Molecular Chaperone Regulator 5; KIAA0873;

Entrez Gene ID

9529

UniProt ID

Q9UL15

More Infomation

References

Wang, J. M., Gao, Q., Zhang, Q., Hao, L., Jiang, J. Y., Huyan, L. Y., ... & Wang, H. Q. (2021). Implication of BAG5 downregulation in metabolic reprogramming of cisplatin-resistant ovarian cancer cells via mTORC2 signaling pathway. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 119076.

Friesen, E. L., Zhang, Y. T., Earnshaw, R., De Snoo, M. L., O’Hara, D. M., Agapova, V., ... & Kalia, S. K. (2020). BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62. Frontiers in Cell and Developmental Biology, 8, 716.

Zhang, D. L., Wang, J. M., Wu, T., Du, X., Yan, J., Du, Z. X., & Wang, H. Q. (2020). BAG5 promotes invasion of papillary thyroid cancer cells via upregulation of fibronectin 1 at the translational level. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1867(9), 118715.

Chen, H. Y., Lin, C. H., & Teng, S. C. (2020). Stress-induced p53 drives BAG5 cochaperone expression to control α-synuclein aggregation in Parkinson's disease. Aging (Albany NY), 12(20), 20702.

De Snoo, M. L., Friesen, E. L., Zhang, Y. T., Earnshaw, R., Dorval, G., Kapadia, M., ... & Kalia, S. K. (2019). Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell death & disease, 10(12), 1-14.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

BAG5 Matched Antibody Pair (124)

Antibody Pairs

BAG5 Matched Antibody Pair (124)

Related Products

Mouse Anti-BAG5 Recombinant Antibody (CBYY-0166)

BAG5 Matched Antibody Pair (124)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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