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CALCR Matched Antibody Pair (168) (APMAB-168LY)

This antibody pair set can be used for detecting and quantifying protein level of human CALCR.
See all CALCR antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CALCR monoclonal antibody, 100 ug
Detection Antibody
Anti-CALCR Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Alternative Names
Calcitonin Receptor; CT-R; CTR1; CRT; CTR;
Entrez Gene ID
799
UniProt ID
P30988

Zhang, L., Kubota, M., Nakamura, A., Kaji, T., Seno, S., Uezumi, A., ... & Fukada, S. I. (2021). Dlk1 regulates quiescence in calcitonin receptor‐mutant muscle stem cells. Stem Cells, 39(3), 306-317.

Gonzalez, I. E., Ramirez-Matias, J., Lu, C., Pan, W., Zhu, A., Myers Jr, M. G., & Olson, D. P. (2021). Paraventricular Calcitonin Receptor–Expressing Neurons Modulate Energy Homeostasis in Male Mice. Endocrinology, 162(6), bqab072.

Yoshihara, C., Tokita, K., Maruyama, T., Kaneko, M., Tsuneoka, Y., Fukumitsu, K., ... & Kuroda, K. O. (2021). Calcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care. Cell Reports, 35(9), 109204.

Cheng, W., Gonzalez, I., Pan, W., Tsang, A. H., Adams, J., Ndoka, E., ... & Myers Jr, M. G. (2020). Calcitonin receptor neurons in the mouse nucleus tractus solitarius control energy balance via the non-aversive suppression of feeding. Cell metabolism, 31(2), 301-312.

Ikemoto‐Uezumi, M., Uezumi, A., Zhang, L., Zhou, H., Hashimoto, N., Okamura, K., ... & Fukada, S. I. (2019). Reduced expression of calcitonin receptor is closely associated with age‐related loss of the muscle stem cell pool. JCSM Rapid Communications, 2(1), 1-13.

Ieda, N., Kawai, N., Ishii, H., Ihara, K., Inoue, N., Uenoyama, Y., & Tsukamura, H. (2018). Co‐expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats. Reproductive medicine and biology, 17(2), 164-172.

Pan, W., Adams, J. M., Allison, M. B., Patterson, C., Flak, J. N., Jones, J., ... & Myers Jr, M. G. (2018). Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin. Endocrinology, 159(4), 1860-1872.

Pal, J., Patil, V., Kumar, A., Kaur, K., Sarkar, C., & Somasundaram, K. (2018). Loss-of-function mutations in Calcitonin receptor (CALCR) identify highly aggressive glioblastoma with poor outcome. Clinical Cancer Research, 24(6), 1448-1458.

Mitra, P., Guha, M., Ghosh, S., Mukherjee, S., Bankura, B., Pal, D. K., ... & Das, M. (2017). Association of calcitonin receptor gene (CALCR) polymorphism with kidney stone disease in the population of West Bengal, India. Gene, 622, 23-28.

Yuan, J., Gilbert, E. R., & Cline, M. A. (2017). The central anorexigenic mechanism of amylin in Japanese quail (Coturnix japonica) involves pro-opiomelanocortin, calcitonin receptor, and the arcuate nucleus of the hypothalamus. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 210, 28-34.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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