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CAP1 Matched Antibody Pair (180) (APMAB-180LY)

This antibody pair set can be used for detecting and quantifying protein level of human CAP1.
See all CAP1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CAP1 monoclonal antibody, 100 ug
Detection Antibody
Anti-CAP1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CAP1 (Cyclase Associated Actin Cytoskeleton Regulatory Protein 1) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Signaling by Robo receptor. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is CAP2.
Alternative Names
Cyclase Associated Actin Cytoskeleton Regulatory Protein 1; Adenylate Cyclase Associated Protein 1; CAP; CAP, Adenylate Cyclase-Associated Protein 1 (Yeast); Testis Secretory Sperm-Binding Protein Li 218p; CAP, Adenylate Cyclase-Associated Protein 1; Adenylyl Cyclase-Associated Protein 1; CAP1-PEN; CAP 1;
Entrez Gene ID
10487
UniProt ID
Q01518

Schneider, F., Duong, T. A., Metz, I., Winkelmeier, J., Hübner, C. A., Endesfelder, U., & Rust, M. B. (2021). Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function. Progress in Neurobiology, 202, 102050.

Zhang, X., Pizzoni, A., Hong, K., Naim, N., Qi, C., Korkhov, V., & Altschuler, D. L. (2021). CAP1 binds and activates adenylyl cyclase in mammalian cells. Proceedings of the National Academy of Sciences, 118(24).

Zhang, H., Ramsey, A., Xiao, Y., Karki, U., Xie, J. Y., Xu, J., ... & Zhou, G. L. (2020). Dynamic phosphorylation and dephosphorylation of cyclase-associated protein 1 by antagonistic signaling through cyclin-dependent kinase 5 and cAMP are critical for the protein functions in actin filament disassembly and cell adhesion. Molecular and cellular biology, 40(4), e00282-19.

Bergqvist, M., Elebro, K., Sandsveden, M., Borgquist, S., & Rosendahl, A. H. (2020). Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer. Breast Cancer Research, 22(1), 1-15.

Yuan, X., Zhen, Z., Zhang, M., Yu, Y., Gao, X., & Ao, J. X. (2019). Cyclase‐associated protein 1 is a key negative regulator of milk synthesis and proliferation of bovine mammary epithelial cells. Cell biochemistry and function, 37(3), 185-192.

Hasan, R., & Zhou, G. L. (2019). The cytoskeletal protein cyclase-associated protein 1 (CAP1) in breast cancer: context-dependent roles in both the invasiveness and proliferation of cancer cells and underlying cell signals. International journal of molecular sciences, 20(11), 2653.

Wu, H., Hasan, R., Zhang, H., Gray, J., Williams, D., Miller, M., ... & Zhou, G. L. (2019). Phosphorylation regulates CAP1 (cyclase-associated protein 1) functions in the motility and invasion of pancreatic cancer cells. Scientific reports, 9(1), 1-13.

Kakurina, G. V., Kolegova, E. S., & Kondakova, I. V. (2018). Adenylyl cyclase-associated protein 1: structure, regulation, and participation in cellular processes. Biochemistry (Moscow), 83(1), 45-53.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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