Cattle IL5 ELISA Kit (V2LY-0626-LY2568)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0051 ng/mL
Detection Range
0.01-2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Cattle
Assay Type
Sandwich
Reactivity
Cattle
Assay Time
1.5 h
Molecule Mass
15.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Interleukin 5
Alternative Names
Interleukin 5
Function
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Biological Process
Cytokine-mediated signaling pathwayIEA:Ensembl
Immune responseIEA:InterPro
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of B cell proliferationIEA:Ensembl
Positive regulation of DNA-binding transcription factor activityIEA:Ensembl
Positive regulation of eosinophil differentiationIEA:Ensembl
Positive regulation of immunoglobulin productionIEA:Ensembl
Positive regulation of peptidyl-tyrosine phosphorylationISS:UniProtKB
Positive regulation of podosome assemblyManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of receptor signaling pathway via JAK-STATIEA:Ensembl
Positive regulation of transcription, DNA-templatedIEA:Ensembl
Cellular Location
Secreted

Maglio, A., Vitale, C., Pelaia, C., D’Amato, M., Ciampo, L., Sferra, E., ... & Vatrella, A. (2023). Severe asthma remissions induced by biologics targeting IL5/IL5r: results from a multicenter real-life study. International Journal of Molecular Sciences, 24(3), 2455.

Van Hulst, G., Jorssen, J., Jacobs, N., Henket, M., Louis, R., Schleich, F., ... & Desmet, C. J. (2022). Anti-IL5 mepolizumab minimally influences residual blood eosinophils in severe asthma. European Respiratory Journal, 59(3).

Mümmler, C., Suhling, H., Walter, J., Kneidinger, N., Buhl, R., Kayser, M. Z., ... & Milger, K. (2022). Overall Response to Anti-IL-5/Anti-IL5-Rα Treatment in Severe Asthma Does Not Depend on Initial Bronchodilator Responsiveness. The Journal of Allergy and Clinical Immunology: In Practice, 10(12), 3174-3183.

Pala, D., & Pistis, M. (2021). Anti-IL5 drugs in COVID-19 patients: role of eosinophils in SARS-CoV-2-induced immunopathology. Frontiers in pharmacology, 12, 622554.

Bjerrum, A. S., Skjold, T., & Schmid, J. M. (2021). Oral corticosteroid sparing effects of anti-IL5/anti-IL5 receptor treatment after 2 years of treatment. Respiratory Medicine, 176, 106260.

Martínez-Moragón, E., García-Moguel, I., Nuevo, J., & Resler, G. (2021). Real-world study in severe eosinophilic asthma patients refractory to anti-IL5 biological agents treated with benralizumab in Spain (ORBE study). BMC Pulmonary Medicine, 21(1), 1-12.

Menzella, F., Ruggiero, P., Ghidoni, G., Fontana, M., Bagnasco, D., Livrieri, F., ... & Facciolongo, N. (2020). Anti-IL5 therapies for severe eosinophilic asthma: literature review and practical insights. Journal of Asthma and Allergy, 301-313.

Rademacher, J., Konwert, S., Fuge, J., Dettmer, S., Welte, T., & Ringshausen, F. C. (2020). Anti-IL5 and anti-IL5Rα therapy for clinically significant bronchiectasis with eosinophilic endotype: a case series. European Respiratory Journal, 55(1).

Marc-Malovrh, M., Camlek, L., Škrgat, S., Kern, I., Fležar, M., Dežman, M., & Korošec, P. (2020). Elevated eosinophils, IL5 and IL8 in induced sputum in asthma patients with accelerated FEV1 decline. Respiratory Medicine, 162, 105875.

Ramonell, R. P., & Iftikhar, I. H. (2020). Effect of anti-IL5, anti-IL5R, anti-IL13 therapy on asthma exacerbations: a network meta-analysis. Lung, 198, 95-103.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Canine Recombinant IL5 protein, His Tag (CAT#: V2LY-0526-LY1288)

Cynomolgus Recombinant IL5 protein, His Tag (CAT#: V2LY-0526-LY1578)

Human Recombinant IL5 protein (CAT#: V2LY-0526-LY4933)

Human Recombinant IL5 protein-1 (CAT#: V2LY-0526-LY4934)

Human Recombinant IL5 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4935)

Human Recombinant IL5 protein, His Tag (CAT#: V2LY-0526-LY4936)

Human Recombinant IL5 protein, Fc Tag (CAT#: V2LY-0526-LY4937)

Mouse Recombinant IL5 protein, His Tag (CAT#: V2LY-0526-LY8549)

Mouse Il5 ELISA Kit (CAT#: V2LY-0626-LY246)

Sheep IL5 ELISA Kit (CAT#: V2LY-0626-LY256)

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Human Recombinant IL5 protein (CAT#: V2LY-0526-LY4933)

Rat Anti-IL5 Recombinant Antibody (TRFK5) (CAT#: CBMAB-I1118-YY)

Rat Anti-IL5 Recombinant Antibody (JES1-39D10) (CAT#: CBMAB-I0592-YY)

Rat Anti-IL5 Recombinant Antibody (JES1-5A10) (CAT#: CBMAB-I0593-YY)

Mouse Anti-IL5 Recombinant Antibody (CBYY-I0800) (CAT#: CBMAB-I1781-YY)

Rat Anti-IL5 Recombinant Antibody (CBYY-I0651) (CAT#: CBMAB-I1464-YY)

Human Recombinant IL5 protein-1 (CAT#: V2LY-0526-LY4934)

Rat Il5 ELISA Kit (CAT#: V2LY-0626-LY449)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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