CD27 Matched Antibody Pair (213) (APMAB-213LY)

Name: CD27 Matched Antibody Pair (213)
SKU: APMAB-213LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CD27 polyclonal antibody, 100 ug

Detection Antibody

Anti-CD27 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

CD27 (CD27 Molecule) is a Protein Coding gene. Diseases associated with CD27 include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Disease. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and cysteine-type endopeptidase inhibitor activity involved in apoptotic process.

Alternative Names

CD27 Molecule; Tumor Necrosis Factor Receptor Superfamily, Member 7; T-Cell Activation Antigen CD27; CD27L Receptor; CD27 Antigen; TNFRSF7; T14;

Entrez Gene ID

939

UniProt ID

P26842

More Infomation

Xu, F., Zhang, H., Si, X., Chen, J., Chen, Y., Cui, X., & Qin, Y. (2021). Assessment of CD27 expression on T-cells as a diagnostic and therapeutic tool for patients with smear-negative pulmonary tuberculosis. BMC immunology, 22(1), 1-8.

Deng, Y., Chatterjee, B., Zens, K., Zdimerova, H., Müller, A., Schuhmachers, P., ... & Münz, C. (2021). CD27 is required for protective lytic EBV antigen–specific CD8+ T-cell expansion. Blood, The Journal of the American Society of Hematology, 137(23), 3225-3236.

Rojas, J. M., Alejo, A., Avia, J. M., Rodríguez-Martín, D., Sánchez, C., Alcamí, A., ... & Martín, V. (2020). Activation of OX40 and CD27 costimulatory signalling in sheep through recombinant ovine ligands. Vaccines, 8(2), 333.

Nevalainen, T., Autio, A., Kummola, L., Salomaa, T., Junttila, I., Jylhä, M., & Hurme, M. (2019). CD27-IgD-B cell memory subset associates with inflammation and frailty in elderly individuals but only in males. Immunity & Ageing, 16(1), 1-9.

Starzer, A. M., & Berghoff, A. S. (2019). New emerging targets in cancer immunotherapy: CD27 (TNFRSF7). ESMO open, 4, e000629.

Centuori, S. M., Gomes, C. J., Kim, S. S., Putnam, C. W., Larsen, B. T., Garland, L. L., ... & Martinez, J. D. (2018). Double-negative (CD27− IgD−) B cells are expanded in NSCLC and inversely correlate with affinity-matured B cell populations. Journal of translational medicine, 16(1), 1-8.

Alaterre, E., Raimbault, S., Goldschmidt, H., Bouhya, S., Requirand, G., Robert, N., ... & Moreaux, J. (2017). CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma. Oncotarget, 8(58), 98931.

Burris, H. A., Infante, J. R., Ansell, S. M., Nemunaitis, J. J., Weiss, G. R., Villalobos, V. M., ... & Carson, W. E. (2017). Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, in patients with advanced solid tumors. J Clin Oncol, 35(18), 2028-2036.

Chen, D., Gerasimčik, N., Camponeschi, A., Tan, Y., Wu, Q., Brynjolfsson, S., ... & Mårtensson, I. L. (2017). CD27 expression and its association with clinical outcome in children and adults with pro-B acute lymphoblastic leukemia. Blood cancer journal, 7(6), e575-e575.

Bullock, T. N. (2017). Stimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer. Current opinion in immunology, 45, 82-88.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CD27 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2750)

Human Recombinant CD27 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY2751)

Human Recombinant CD27 protein, His Tag (CAT#: V2LY-0526-LY2752)

Human Recombinant CD27 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY2753)

Human Recombinant CD27 protein, His Tag-1 (CAT#: V2LY-0526-LY2754)

Human Recombinant CD27 protein, rFc Tag (CAT#: V2LY-0526-LY2755)

Mouse Recombinant CD27 protein, ECD, Fc Tag (CAT#: V2LY-0526-LY7981)

Mouse Recombinant CD27 protein, His & hFc Tag (CAT#: V2LY-0526-LY7982)

Mouse Recombinant CD27 protein, His Tag (CAT#: V2LY-0526-LY7983)

Rat Recombinant CD27 protein, hFc Tag (CAT#: V2LY-0526-LY9223)

Related Products

Mouse Recombinant CD27 protein, His Tag (CAT#: V2LY-0526-LY7983)

Rat Recombinant CD27 protein, hFc Tag (CAT#: V2LY-0526-LY9223)

Mouse Anti-CD27 Recombinant Antibody (CBT4261) (CAT#: V2LY-0625-LY1222)

Rat Recombinant CD27 protein, Fc Tag (CAT#: V2LY-0526-LY9224)

Rabbit Anti-CD27 Recombinant Antibody (CBFYC-0111) (CAT#: CBMAB-C0128-FY)

Rat Anti-CD27 Recombinant Antibody (137915) (CAT#: CBMAB-C0305-LY)

Rat Anti-CD27 Recombinant Antibody (137910) (CAT#: CBMAB-C0304-LY)

Human Recombinant CD27 protein, His Tag (CAT#: V2LY-0526-LY2752)

Rhesus Recombinant CD27 protein, hFc Tag (CAT#: V2LY-0526-LY9672)

Human Recombinant CD27 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY2753)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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