CD276 Matched Antibody Pair (215) (APMAB-215LY)

Name: CD276 Matched Antibody Pair (215)
SKU: APMAB-215LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-CD276 monoclonal, IgG1 antibody, 100 ug

Detection Antibody

Anti-CD276 Biotinylated mouse monoclonal, IgG1 antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

CD276 (CD276 Molecule) is a Protein Coding gene. Diseases associated with CD276 include Neuroblastoma and Acute Cervicitis. Among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.

Alternative Names

CD276 Molecule; CD276 Antigen; Costimulatory Molecule; B7 Homolog 3; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2;

Entrez Gene ID

80381

UniProt ID

Q5ZPR3

More Infomation

Fu, M., Zhang, J., Li, W., He, S., Zhang, J., Tennant, D., ... & Mao, Y. (2021). Gene Clusters Based on OLIG2 and CD276 Could Distinguish Molecular Profiling in Glioblastoma.

Wang, M. Y., Qi, B., Wang, F., Lin, Z. R., Li, M. Y., Yin, W. J., ... & Chen, D. P. (2021). PBK phosphorylates MSL1 to elicit epigenetic modulation of CD276 in nasopharyngeal carcinoma. Oncogenesis, 10(1), 1-14.

Liu, X., Zhelev, D., Adams, C., Chen, C., Mellors, J. W., & Dimitrov, D. S. (2021). Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibody. Translational oncology, 14(12), 101232.

Kanchan, R. K., Perumal, N., Atri, P., Chirravuri Venkata, R., Thapa, I., Klinkebiel, D. L., ... & Mahapatra, S. (2020). MiR‐1253 exerts tumor‐suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7‐H3). Brain Pathology, 30(4), 732-745.

Li, R., Zatloukalova, P., Muller, P., Gil-Mir, M., Kote, S., Wilkinson, S., ... & Vojtesek, B. (2020). The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276. Cellular & molecular biology letters, 25(1), 1-21.

Cheng, R., Wang, B., Cai, X. R., Chen, Z. S., Du, Q., Zhou, L. Y., ... & Chen, Y. L. (2020). CD276 promotes vasculogenic mimicry formation in hepatocellular carcinoma via the PI3K/AKT/MMPs pathway. OncoTargets and therapy, 13, 11485.

Yu, X., Wei, B., Su, R., Yao, J., Feng, X., Jiang, G., ... & Zhou, L. (2019). A risk assessment model of acute liver allograft rejection by genetic polymorphism of CD 276. Molecular genetics & genomic medicine, 7(6), e689.

Son, Y., Kwon, S. M., & Cho, J. Y. (2019). CD276 (B7‐H3) Maintains Proliferation and Regulates Differentiation in Angiogenic Function in Late Endothelial Progenitor Cells. Stem Cells, 37(3), 382-394.

Bao, R., Wang, Y., Lai, J., Zhu, H., Zhao, Y., Li, S., ... & Liu, Z. (2018). Enhancing anti-PD-1/PD-L1 immune checkpoint inhibitory cancer therapy by CD276-targeted photodynamic ablation of tumor cells and tumor vasculature. Molecular pharmaceutics, 16(1), 339-348.

Hwang, J. Y., Jeong, J. M., Kwon, M. G., Seo, J. S., Hwang, S. D., Son, M. H., ... & Park, C. I. (2018). Olive flounder CD276 (B7-H3) a coinhibitory molecule for T cells: Responses during viral hemorrhagic septicemia virus (VHSV) stimulation. Fish & shellfish immunology, 73, 228-233.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CD276 protein, ECD, AF488 Conjugated, His Tag (CAT#: V2LY-0526-LY151)

Human Recombinant CD276 protein, ECD, PE Conjugated, His Tag (CAT#: V2LY-0526-LY152)

Cynomolgus Recombinant CD276 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY1382)

Cynomolgus Recombinant CD276 protein, ECD, His Tag (CAT#: V2LY-0526-LY1383)

Cynomolgus Recombinant CD276 protein, ECD, His Tag-1 (CAT#: V2LY-0526-LY1384)

Human Recombinant CD276 protein, APC Conjugated, His Tag (CAT#: V2LY-0526-LY2252)

Human Recombinant CD276 protein, ECD, AF647 Conjugated, His Tag (CAT#: V2LY-0526-LY2253)

Human Recombinant CD276 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2254)

Human Recombinant CD276 protein, ECD, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY2255)

Human Recombinant CD276 protein, ECD, hFc Tag-1 (CAT#: V2LY-0526-LY2256)

Related Products

Human Recombinant CD276 protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2257)

Mouse Recombinant CD276 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7845)

Mouse Recombinant CD276 protein, ECD, His Tag-1 (CAT#: V2LY-0526-LY7847)

Human Recombinant CD276, isoform 2 protein, ECD, His Tag (CAT#: V2LY-0526-LY2262)

Rat Anti-CD276 Recombinant Antibody (AG18) (CAT#: V2LY-0524-LY96)

Mouse Anti-CD276 Recombinant Antibody (CBYY-1660) (CAT#: CBMAB-2009-YY)

Rat Anti-CD276 Recombinant Antibody (MJ18) (CAT#: CBMAB-C3060-CQ)

Mouse Anti-CD276 Recombinant Antibody (CBYY-0972) (CAT#: CBMAB-0975-YY)

Human Recombinant CD276 protein, ECD, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY2255)

Human Recombinant CD276 protein, ECD, AF647 Conjugated, His Tag (CAT#: V2LY-0526-LY2253)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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