DDIT4 Matched Antibody Pair (331) (APMAB-331LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-DDIT4 polyclonal antibody, 100 ug
Detection Antibody
Anti-DDIT4 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
DDIT4 (DNA Damage Inducible Transcript 4) is a Protein Coding gene. Among its related pathways are Gene Expression and Direct p53 effectors. Gene Ontology (GO) annotations related to this gene include 14-3-3 protein binding. An important paralog of this gene is DDIT4L.
Alternative Names
DNA Damage Inducible Transcript 4; Protein Regulated In Development And DNA Damage Response 1; HIF-1 Responsive Protein RTP801; REDD-1; REDD1; DNA Damage-Inducible Transcript 4 Protein;
Entrez Gene ID
UniProt ID
More Infomation

Fattahi, F., Saeednejad Zanjani, L., Habibi Shams, Z., Kiani, J., Mehrazma, M., Najafi, M., & Madjd, Z. (2021). High expression of DNA damage-inducible transcript 4 (DDIT4) is associated with advanced pathological features in the patients with colorectal cancer. Scientific Reports, 11(1), 1-17.

Miao, Z. F., Sun, J. X., Adkins-Threats, M., Pang, M. J., Zhao, J. H., Wang, X., ... & Mills, J. C. (2021). DDIT4 licenses only healthy cells to proliferate during injury-induced metaplasia. Gastroenterology, 160(1), 260-271.

Ho, K. H., Chen, P. H., Chou, C. M., Shih, C. M., Lee, Y. T., Cheng, C. H., & Chen, K. C. (2020). A key role of DNA damage-inducible transcript 4 (DDIT4) connects autophagy and GLUT3-mediated stemness to desensitize temozolomide efficacy in glioblastomas. Neurotherapeutics, 17(3), 1212-1227.

Zhang, X., Luo, F., Li, J., Wan, J., Zhang, L., Li, H., ... & Zhao, H. (2019). DNA damage‐inducible transcript 4 is an innate guardian for human squamous cell carcinoma and an molecular vector for anti‐carcinoma effect of 1, 25 (OH) 2D3. Experimental dermatology, 28(1), 45-52.

Foltyn, M., Luger, A. L., Lorenz, N. I., Sauer, B., Mittelbronn, M., Harter, P. N., ... & Ronellenfitsch, M. W. (2019). The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma. British journal of cancer, 120(5), 481-487.

Tirado-Hurtado, I., Fajardo, W., & Pinto, J. A. (2018). DNA damage inducible transcript 4 gene: the switch of the metabolism as potential target in cancer. Frontiers in oncology, 8, 106.

Yang, J., Zhang, Y., Tong, J., Lv, H., Zhang, C., & Chen, Z. J. (2018). Dysfunction of DNA damage-inducible transcript 4 in the decidua is relevant to the pathogenesis of preeclampsia. Biology of Reproduction, 98(6), 821-833.

Du, F., Sun, L., Chu, Y., Li, T., Lei, C., Wang, X., ... & Fan, D. (2018). DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways. Cancer Communications, 38(1), 1-14.

Zhang, F., Liu, G., Li, D., Wei, C., & Hao, J. (2018). DDIT4 and associated lncDDIT4 modulate Th17 differentiation through the DDIT4/TSC/mTOR pathway. The Journal of Immunology, 200(5), 1618-1626.

Pinto, J. A., Rolfo, C., Raez, L. E., Prado, A., Araujo, J. M., Bravo, L., ... & Gomez, H. L. (2017). In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies. Scientific reports, 7(1), 1-11.

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For research use only. Not intended for any clinical use.

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