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ELK3 Matched Antibody Pair (374) (APMAB-374LY)

This antibody pair set can be used for detecting and quantifying protein level of human ELK3.
See all ELK3 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ELK3 monoclonal antibody, 100 ug
Detection Antibody
Anti-ELK3 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Alternative Names
ELK3, ETS Transcription Factor; SRF Accessory Protein 2; ELK3, ETS-Domain Protein (SRF Accessory Protein 2); Serum Response Factor Accessory Protein 2; ETS-Related Protein ERP; ETS-Related Protein NET;
Entrez Gene ID
2004
UniProt ID
P41970

Ma, S., Wang, H., Li, W., Yan, Z., Luo, X., & Lu, P. (2022). RREB1 promotes the development of parafollicular carcinogenesis through the Ras-Raf-1-ELK3 signaling pathway. Nucleosides, Nucleotides & Nucleic Acids, 1-10.

Liu, N., He, J., Fan, D., Gu, Y., Wang, J., Li, H., ... & Fan, Z. (2022). Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription. Nature communications, 13(1), 1-14.

Zhang, J., Song, H., Chen, C., Chen, L., Dai, Y., Sun, P. H., ... & Wang, X. (2021). Methyltransferase-like protein 11A promotes migration of cervical cancer cells via up-regulating ELK3. Pharmacological Research, 172, 105814.

Mao, Y., Li, W., Hua, B., Gu, X., Pan, W., Chen, Q., ... & Lu, C. (2020). Silencing of ELK3 induces SM phase arrest and apoptosis and upregulates SERPINE1 expression reducing migration in prostate cancer cells. BioMed Research International, 2020.

Meng, L., Xing, Z., Guo, Z., & Liu, Z. (2020). LINC01106 post-transcriptionally regulates ELK3 and HOXD8 to promote bladder cancer progression. Cell death & disease, 11(12), 1-15.

Kim, H. K., Park, J. D., Choi, S. H., Shin, D. J., Hwang, S., Jung, H. Y., & Park, K. S. (2020). Functional link between miR-200a and ELK3 regulates the metastatic nature of breast cancer. Cancers, 12(5), 1225.

Wang, S., Li, J., & Yang, X. (2019). Long non-coding RNA LINC00525 promotes the stemness and chemoresistance of colorectal cancer by targeting miR-507/ELK3 axis. International journal of stem cells, 12(2), 347-359.

Kim, K. S., Park, J. I., Oh, N., Cho, H. J., Park, J. H., & Park, K. S. (2019). ELK3 expressed in lymphatic endothelial cells promotes breast cancer progression and metastasis through exosomal miRNAs. Scientific reports, 9(1), 1-10.

Cho, H. J., Oh, N., Park, J. H., Kim, K. S., Kim, H. K., Lee, E., ... & Park, K. S. (2019). ZEB1 Collaborates with ELK3 to Repress E-Cadherin Expression in Triple-Negative Breast Cancer CellsZEB1 and ELK3 Complex Targets E-Cadherin in Breast Cancer. Molecular Cancer Research, 17(11), 2257-2266.

Yoo, S. M., Lee, C. J., An, H. J., Lee, J. Y., Lee, H. S., Kang, H. C., ... & Cho, Y. Y. (2019). RSK2-mediated ELK3 activation enhances cell transformation and breast cancer cell growth by regulation of c-fos promoter activity. International journal of molecular sciences, 20(8), 1994.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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