ELK3

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Full Name
ELK3, ETS Transcription Factor
Research Area
May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.
Biological Process
Angiogenesis Source: Ensembl
Cell differentiation Source: GO_Central
Negative regulation of transcription, DNA-templated Source: HGNC-UCL
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Signal transduction Source: ProtInc
Wound healing Source: Ensembl
Cellular Location
Nucleus
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Anti-ELK3 antibodies

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ELK3 Matched Antibody Pair (374) (APMAB-374LY)

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Target: ELK3
Specificity: Human
Datasheet SDS

Mouse Anti-ELK3 Recombinant Antibody (3A12) (CBMAB-A2575-LY)

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Target: ELK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A12
Application*: WB, E
Datasheet SDS

Mouse Anti-ELK3 Recombinant Antibody (CBFYE-0784) (CBMAB-E1229-FY)

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Target: ELK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYE-0784
Application*: WB, IH, IF, F
Datasheet SDS

Mouse Anti-ELK3 Recombinant Antibody (CBFYE-0783) (CBMAB-E1228-FY)

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Target: ELK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYE-0783
Application*: WB, E, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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