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ENO1 Matched Antibody Pair (378) (APMAB-378LY)

This antibody pair set can be used for detecting and quantifying protein level of human ENO1.
See all ENO1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ENO1 monoclonal, IgG1 antibody, 100 ug
Detection Antibody
Anti-ENO1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Alternative Names
Enolase 1; 2-Phospho-D-Glycerate Hydro-Lyase; Plasminogen-Binding Protein; Phosphopyruvate Hydratase; Enolase 1, (Alpha); Non-Neural Enolase; Alpha-Enolase; EC 4.2.1.11; ENO1L1; MPB1; NNE; Epididymis Secretory Protein Li 17; C-Myc Promoter-Binding Protein-1;
Entrez Gene ID
UniProt ID

Huppertz, I., Perez-Perri, J. I., Mantas, P., Sekaran, T., Schwarzl, T., Russo, F., ... & Hentze, M. W. (2022). Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. Molecular Cell, 82(14), 2666-2680.

Qiao, G., Wu, A., Chen, X., Tian, Y., & Lin, X. (2021). Enolase 1, a moonlighting protein, as a potential target for cancer treatment. International journal of biological sciences, 17(14), 3981.

Xu, W., Yang, W., Wu, C., Ma, X., Li, H., & Zheng, J. (2021). Enolase 1 correlated with cancer progression and immune-infiltrating in multiple cancer types: a pan-cancer analysis. Frontiers in oncology, 10, 593706.

Yang, T., Shu, X., Zhang, H. W., Sun, L. X., Yu, L., Liu, J., ... & Ran, Y. L. (2020). Enolase 1 regulates stem cell-like properties in gastric cancer cells by stimulating glycolysis. Cell Death & Disease, 11(10), 1-13.

Chen, J. M. M., Chiu, S. C., Chen, K. C., Huang, Y. R. J., Liao, Y. T. A., & Yu, C. T. R. (2020). Enolase 1 differentially contributes to cell transformation in lung cancer but not in esophageal cancer. Oncology letters, 19(4), 3189-3196.

Didiasova, M., Schaefer, L., & Wygrecka, M. (2019). When place matters: shuttling of enolase-1 across cellular compartments. Frontiers in cell and developmental biology, 7, 61.

Cancemi, P., Buttacavoli, M., Roz, E., & Feo, S. (2019). Expression of alpha-enolase (ENO1), myc promoter-binding protein-1 (MBP-1) and matrix metalloproteinases (MMP-2 and MMP-9) reflect the nature and aggressiveness of breast tumors. International journal of molecular sciences, 20(16), 3952.

Lee, J. Y., Kang, M. J., Choi, J. Y., Park, J. S., Park, J. K., Lee, E. Y., ... & Song, Y. W. (2018). Apolipoprotein B binds to enolase-1 and aggravates inflammation in rheumatoid arthritis. Annals of the Rheumatic Diseases, 77(10), 1480-1489.

Zhu, W., Li, H., Yu, Y., Chen, J., Chen, X., Ren, F., ... & Cui, G. (2018). Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients. Cancer management and research, 10, 5735.

Liu, Y., Li, H., Liu, Y., & Zhu, Z. (2018). MiR-22-3p targeting alpha-enolase 1 regulates the proliferation of retinoblastoma cells. Biomedicine & Pharmacotherapy, 105, 805-812.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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