EPHA2 Matched Antibody Pair (382) (APMAB-382LY)

Name: EPHA2 Matched Antibody Pair (382)
SKU: APMAB-382LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-EPHA2 polyclonal antibody, 100 ug

Detection Antibody

Anti-EPHA2 Mouse polyclonal antibody, 40 ul

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]

Alternative Names

EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Ephrin Type-A Receptor 2; Soluble EPHA2 Variant 1; Epithelial Cell Kinase;

Entrez Gene ID

1969

UniProt ID

P29317

More Infomation

Wallaschek, N., Reuter, S., Silkenat, S., Wolf, K., Niklas, C., Kayisoglu, Ö., ... & Bartfeld, S. (2021). Ephrin receptor A2, the epithelial receptor for Epstein-Barr virus entry, is not available for efficient infection in human gastric organoids. PLoS pathogens, 17(2), e1009210.

Wang, H., & Qiu, W. (2021). EPHA2, a promising therapeutic target for hepatocellular carcinoma. Molecular & Cellular Oncology, 8(3), 1910009.

Ieguchi, K., & Maru, Y. (2019). Roles of EphA1/A2 and ephrin‐A1 in cancer. Cancer science, 110(3), 841-848.

Chen, J., Sathiyamoorthy, K., Zhang, X., Schaller, S., Perez White, B. E., Jardetzky, T. S., & Longnecker, R. (2018). Ephrin receptor A2 is a functional entry receptor for Epstein–Barr virus. Nature microbiology, 3(2), 172-180.

Peng, Q., Chen, L., Wu, W., Wang, J., Zheng, X., Chen, Z., ... & Ma, J. (2018). EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer. Cell death & disease, 9(12), 1-16.

Zhang, H., Li, Y., Wang, H. B., Zhang, A., Chen, M. L., Fang, Z. X., ... & Zeng, M. S. (2018). Ephrin receptor A2 is an epithelial cell receptor for Epstein–Barr virus entry. Nature microbiology, 3(2), 1-8.

Qazi, M. A., Vora, P., Venugopal, C., Adams, J., Singh, M., Hu, A., ... & Singh, S. K. (2018). Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent GlioblastomaTargeting EphA2 and EphA3 in Recurrent GBM. Cancer Research, 78(17), 5023-5037.

Langlois, A. C., Marinach, C., Manzoni, G., & Silvie, O. (2018). Plasmodium sporozoites can invade hepatocytic cells independently of the Ephrin receptor A2. PLoS One, 13(7), e0200032.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant EPHA2 protein, GST Tag (CAT#: V2LY-0526-LY3873)

Human Recombinant EPHA2 protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY3874)

Human Recombinant EPHA2, Active protein, GST Tag (CAT#: V2LY-0526-LY3875)

Human Recombinant EPHA2 protein, hFc Tag (CAT#: V2LY-0526-LY3876)

Human Recombinant EPHA2 protein, hFc Tag-1 (CAT#: V2LY-0526-LY3877)

Human Recombinant EPHA2 protein, His Tag (CAT#: V2LY-0526-LY3878)

Mouse Recombinant EPHA2 proteinECD (CAT#: V2LY-0526-LY8236)

Mouse Recombinant EPHA2 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY8237)

Mouse Recombinant EPHA2 protein, His Tag (CAT#: V2LY-0526-LY8238)

Human EPHA2 ELISA Kit (CAT#: V2LY-0626-LY4548)

Antibody Pairs

EPHA2 Matched Antibody Pair (383) (CAT#: APMAB-383LY)

EPHA2 Matched Antibody Pair (384) (CAT#: APMAB-384LY)

Related Products

Mouse Anti-EPHA2 Recombinant Antibody (CBFYE-0975) (CAT#: CBMAB-E1460-FY)

Human Recombinant EPHA2 protein, hFc Tag (CAT#: V2LY-0526-LY3876)

Mouse Anti-EphA2 Recombinant Antibody (CBT4164) (CAT#: V2LY-0625-LY2065)

EPHA2 Matched Antibody Pair (383) (CAT#: APMAB-383LY)

Mouse Recombinant EPHA2 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY8237)

Mouse Recombinant EPHA2 proteinECD (CAT#: V2LY-0526-LY8236)

Rat Anti-EPHA2 Recombinant Antibody (CBFYE-0972) (CAT#: CBMAB-E1456-FY)

Human EPHA2 ELISA Kit (CAT#: V2LY-0626-LY4548)

Human Recombinant EPHA2, Active protein, GST Tag (CAT#: V2LY-0526-LY3875)

Human Recombinant EPHA2 protein, hFc Tag-1 (CAT#: V2LY-0526-LY3877)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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