FAS Matched Antibody Pair (410) (APMAB-410LY)

Name: FAS Matched Antibody Pair (410)
SKU: APMAB-410LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-FAS monoclonal antibody, 100 ug

Detection Antibody

Anti-FAS Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]

Alternative Names

Fas Cell Surface Death Receptor; Tumor Necrosis Factor Receptor Superfamily, Member 6; Fas (TNF Receptor Superfamily, Member 6); Apoptosis-Mediating Surface Antigen FAS; TNF Receptor Superfamily Member 6; FASLG Receptor; CD95 Antigen; TNFRSF6; APT1; FAS1; Mutant Tumor Necrosis Receptor Superfamily Member 6;

Entrez Gene ID

355

UniProt ID

P25445

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cattle FAS ELISA Kit (CAT#: V2LY-0626-LY2656)

Cynomolgus Recombinant CD95 protein (CAT#: V2LY-0526-LY1509)

Cynomolgus Recombinant CD95 protein, hFc Tag (CAT#: V2LY-0526-LY1510)

Mouse Recombinant FAS protein, His Tag (CAT#: V2LY-0526-LY8299)

Rat Recombinant FAS protein, hFc Tag (CAT#: V2LY-0526-LY9374)

Rat Recombinant FAS protein, His Tag (CAT#: V2LY-0526-LY9375)

Related Products

Mouse Anti-FAS Recombinant Antibody (CBXF-2570) (CAT#: CBMAB-F0807-CQ)

Mouse Anti-FAS Recombinant Antibody (CBT529) (CAT#: V2LY-0625-LY3444)

Cynomolgus Recombinant CD95 protein (CAT#: V2LY-0526-LY1509)

Mouse Anti-FAS Recombinant Antibody (CBXF-2569) (CAT#: CBMAB-F0157-CQ)

Cynomolgus Recombinant CD95 protein, hFc Tag (CAT#: V2LY-0526-LY1510)

Mouse Anti-FAS Recombinant Antibody (CBT2693) (CAT#: V2LY-0625-LY2702)

Mouse Anti-FAS Recombinant Antibody (CBXF-2853) (CAT#: CBMAB-F0599-CQ)

Rat Recombinant FAS protein, hFc Tag (CAT#: V2LY-0526-LY9374)

Mouse Anti-FAS Recombinant Antibody (CBXF-2858) (CAT#: CBMAB-F0607-CQ)

Mouse Anti-FAS Recombinant Antibody (CBXF-2120) (CAT#: CBMAB-F3017-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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