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FEZ1 Matched Antibody Pair (423) (APMAB-423LY)

This antibody pair set can be used for detecting and quantifying protein level of human FEZ1.
See all FEZ1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-FEZ1 polyclonal antibody, 100 ug
Detection Antibody
Anti-FEZ1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Alternative Names
Fasciculation And Elongation Protein Zeta 1; Zygin I; Zygin-1; Fasciculation And Elongation Protein Zeta-1; UNC-76;
Entrez Gene ID
9638
UniProt ID
Q99689

Razar, R. B. B. A., Qu, Y., Gunaseelan, S., & Chua, J. J. E. (2022). The importance of fasciculation and elongation protein zeta-1 in neural circuit establishment and neurological disorders. Neural Regeneration Research, 17(6), 1165.

Malikov, V., Meade, N., Simons, L. M., Hultquist, J. F., & Naghavi, M. H. (2022). FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression. Cell reports, 38(7), 110396.

Chua, J. Y., Ng, S. J., Yagensky, O., Wanker, E. E., & Chua, J. J. E. (2021). FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development. Eneuro, 8(2).

Zhang, Y., Shi, Q., Li, X., & Xia, C. (2020). Fasciculation and Elongation Protein Zeta-1 Expression in Reactive Astrocytes in a Rat Model of Frontal Lobe Injury. Journal of Neuropathology & Experimental Neurology, 79(2), 194-208.

Demir, M., Yilmaz, U., Colak, C., Cigremis, Y. I. L. M. A. Z., Ozyalin, F., Tekedereli, I., & Sandal, S. (2019). Is there a new pathway relationship between melatonin and FEZ1 in experimental rat model of Alzheimer's disease?. Bratislavske Lekarske Listy, 120(1), 70-77.

Teixeira, M. B., Alborghetti, M. R., & Kobarg, J. (2019). Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity. World Journal of Biological Chemistry, 10(2), 28.

Bertini Teixeira, M., Figueira, A. C. M., Furlan, A. S., Aquino, B., Alborghetti, M. R., Paes Leme, A. F., ... & Kobarg, J. (2018). Fasciculation and elongation zeta‐1 protein (FEZ1) interacts with the retinoic acid receptor and participates in transcriptional regulation of the Hoxb4 gene. FEBS Open bio, 8(1), 4-14.

Alborghetti, M. R. (2018). Proteínas da família FEZ (Fasciculation and Elongation protein Zeta) como adaptadoras bivalentes do transporte= aspectos funcionais, estruturais e evolutivos (Doctoral dissertation, Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia).

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For research use only. Not intended for any clinical use.

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