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FHL2 Matched Antibody Pair (443) (APMAB-443LY)

This antibody pair set can be used for detecting and quantifying protein level of human FHL2.
See all FHL2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-FHL2 polyclonal antibody, 100 ug
Detection Antibody
Anti-FHL2 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]
Alternative Names
Fibrinogen Like 2; Fibrinogen-Like Protein 2; PT49; Fibrinogen-Like 2; Fibroleukin; T49;
Entrez Gene ID
2274
UniProt ID
Q14314

Algaber, A., Madhi, R., Hawez, A., Rönnow, C. F., & Rahman, M. (2021). Targeting FHL2‑E‑cadherin axis by miR‑340‑5p attenuates colon cancer cell migration and invasion. Oncology Letters, 22(2), 1-11.

Clemente-Olivo, M. P., Habibe, J. J., Vos, M., Ottenhoff, R., Jongejan, A., Herrema, H., ... & de Vries, C. J. (2021). Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity. Metabolism, 121, 154815.

Habibe, J. J., Clemente-Olivo, M. P., & de Vries, C. J. (2021). How (Epi) Genetic Regulation of the LIM-Domain Protein FHL2 Impacts Multifactorial Disease. Cells, 10(10), 2611.

Sommer, J., & Hellerbrand, C. (2020). Expression and Function of Four-and-a-Half LIM-domain protein 2 (FHL2) in Hepatocellular Carcinoma. Zeitschrift für Gastroenterologie, 58(01), 4-18.

Wang, C., Lv, X., He, C., Davis, J. S., Wang, C., & Hua, G. (2020). Four and a half lim domains 2 (FHL2) contribute to the epithelial ovarian cancer carcinogenesis. International journal of molecular sciences, 21(20), 7751.

Sommer, J., Dorn, C., Gäbele, E., Bataille, F., Freese, K., Seitz, T., ... & Hellerbrand, C. (2020). Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells, 9(1), 248.

Zhang, L., Li, R., Chen, L., Xing, Z., Song, Y., Nie, X., ... & Tian, S. (2020). Expression, location and biological effects of four and a half LIM domain protein 2 (FHL2) on granulosa cells in ovine. Reproduction in Domestic Animals, 55(6), 737-746.

Sommer, J., Dorn, C., Weiskirchen, R., & Hellerbrand, C. (2020). Expression and Function of Four-and-a-Half LIM-domain protein 2 (FHL2) in Hepatic Fibrosis. Zeitschrift für Gastroenterologie, 58(01), 1-7.

Nishikawa, M., Sato, K., Nakano, S., Yamakawa, H., Nagase, T., & Ueda, H. (2019). Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3. Small GTPases, 10(5), 361-366.

Liang, Y., Bradford, W. H., Zhang, J., & Sheikh, F. (2018). Four and a half LIM domain protein signaling and cardiomyopathy. Biophysical reviews, 10(4), 1073-1085.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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